One Life Brief
July 2006
Recent New Reports Indicate Coffee May Counteract Damage to Liver From Alcohol .
. . but is this good research?
A current One client inquired about a recent report that made headlines across
the country and may have many thinking that a few more cups of coffee will
counteract any negative effects that alcohol might have on the liver. Here is
the inquiry:
"My son just sent me a copy of the recent article
(6/13/06) from a study at Kaiser Permanente regarding the supposedly positive
effects of coffee in preventing cirrhosis of the liver - you may have seen it.
Now, I’m not personally concerned about getting cirrhosis but I wonder, is this
really good research?”
The study suggests that coffee consumption is
associated with a reduced risk of alcoholic cirrhosis. I found the study
interesting and they used enough people (125,000) to make it notable. However,
it is just an “observational study” using medical records indicating alcohol and
coffee habits initially and then following these people’s medical records with
death and hospitalizations as end points. The observational nature of the data
limits any attempt to establish a causal link.
This was not a “prospective double blind case and
control group” type of study that can really pinpoint cause and effect.
Observational studies just show associations. Maybe people who metabolize
caffeine rapidly also metabolize alcohol rapidly and therefore can tolerate more
alcohol and more caffeine, but that doesn’t mean the caffeine protects them. So
for now, until more research is done, I would second the advice of the study’s
co-author, Dr. Arthur Klatsky, who stated that, for those at risk, the better
way to avoid cirrhosis of the liver is “not to drink a lot of coffee but to cut
down on alcohol consumption.” And that is a suggestion that many in the medical
community can agree upon.
- Heather Peña, M.D., Medical Director, St. Helena Center for Health
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